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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOPEY2
All Species:
35.76
Human Site:
Y1578
Identified Species:
60.51
UniProt:
Q9Y3R5
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3R5
NP_005119.2
2298
258184
Y1578
R
E
N
I
S
P
D
Y
P
L
T
L
L
E
G
Chimpanzee
Pan troglodytes
XP_531552
2298
258112
Y1578
R
E
N
I
S
P
D
Y
P
L
T
L
L
E
G
Rhesus Macaque
Macaca mulatta
XP_001084653
2286
256620
Y1566
R
E
N
I
S
P
D
Y
P
L
T
L
L
E
G
Dog
Lupus familis
XP_544874
2297
257913
Y1578
R
E
N
I
S
P
D
Y
P
L
T
L
L
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3UHQ6
2295
257491
Y1577
K
E
N
I
S
P
D
Y
P
L
T
L
L
E
G
Rat
Rattus norvegicus
XP_001055500
2294
257490
Y1576
K
E
N
I
S
P
D
Y
P
L
T
L
L
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512569
2247
251024
L1540
P
L
T
L
L
E
G
L
T
T
I
S
H
F
C
Chicken
Gallus gallus
XP_001232723
2283
257889
Y1564
R
E
N
V
T
P
D
Y
P
L
T
L
L
E
G
Frog
Xenopus laevis
Q642P2
2270
256829
Y1549
R
E
N
V
S
P
D
Y
P
L
T
L
L
E
G
Zebra Danio
Brachydanio rerio
NP_956904
817
86774
T127
S
V
K
P
V
L
L
T
L
Y
E
R
Y
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZBE8
2599
291169
Y1852
Q
R
H
F
P
P
D
Y
V
V
S
Q
L
E
A
Honey Bee
Apis mellifera
XP_395999
2434
273219
F1733
S
Q
Q
I
G
F
S
F
N
Q
P
L
S
G
T
Nematode Worm
Caenorhab. elegans
Q9XW10
2417
267134
I1643
V
G
H
A
M
S
V
I
P
G
S
K
V
A
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03921
1698
194669
Y1008
L
L
S
E
S
I
V
Y
F
E
N
S
I
F
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
94.8
89.9
N.A.
86.4
86.4
N.A.
73.9
75.2
69
21.9
N.A.
27.6
32.1
22.3
N.A.
Protein Similarity:
100
99.7
96
94.6
N.A.
92.4
92.5
N.A.
83
85.4
82
28.7
N.A.
47
53.2
40.9
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
0
86.6
93.3
0
N.A.
33.3
13.3
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
6.6
100
100
0
N.A.
60
26.6
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
0
65
0
0
0
0
0
0
0
0
% D
% Glu:
0
58
0
8
0
8
0
0
0
8
8
0
0
65
0
% E
% Phe:
0
0
0
8
0
8
0
8
8
0
0
0
0
22
0
% F
% Gly:
0
8
0
0
8
0
8
0
0
8
0
0
0
8
58
% G
% His:
0
0
15
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
50
0
8
0
8
0
0
8
0
8
0
0
% I
% Lys:
15
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% K
% Leu:
8
15
0
8
8
8
8
8
8
58
0
65
65
0
8
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
58
0
0
0
0
0
8
0
8
0
0
0
0
% N
% Pro:
8
0
0
8
8
65
0
0
65
0
8
0
0
0
0
% P
% Gln:
8
8
8
0
0
0
0
0
0
8
0
8
0
0
0
% Q
% Arg:
43
8
0
0
0
0
0
0
0
0
0
8
0
0
8
% R
% Ser:
15
0
8
0
58
8
8
0
0
0
15
15
8
0
0
% S
% Thr:
0
0
8
0
8
0
0
8
8
8
58
0
0
0
15
% T
% Val:
8
8
0
15
8
0
15
0
8
8
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
72
0
8
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _